/Other Research Compounds/SLU-PP-332
SLU-PP-332
Research Overview

SLU-PP-332 (4-hydroxy-N'-(naphthalen-2-ylmethylidene)benzohydrazide) is a synthetic small-molecule agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ, orphan nuclear receptors that regulate mitochondrial and oxidative metabolism. It was described in 2023 as a pan-ERR agonist with the highest potency at ERRα and with pharmacokinetic properties suitable for use as an in vivo chemical tool. Published research is preclinical: a skeletal muscle cell line and mice, mouse models of obesity, aged mouse kidney, a mouse pressure overload heart model and primary human myoblasts in culture. Several authors from the originating group have declared holdings in companies developing ERR-targeted compounds. Recent work addresses structure-activity relationships of the scaffold and in vitro metabolite identification for doping control.

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Other Research Compounds

SLU-PP-332

SLU PP 332 · SLUPP-332
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This product is intended for laboratory research purposes only, and is not for human or animal consumption. It is not intended to diagnose, treat, cure, or prevent any disease, and should not be used as a food, drug, cosmetic, or other household product.

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RUO. For research purposes only. Not for human consumption. Not for veterinary use.

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